C.J. Cron hit a tiebreaking two-run homer in the eighth inning, Charlie Blackmon also went deep, and the host Colorado Rockies rallied to beat the San Francisco Giants 5-3 in Denver on Wednesday.

Ryan McMahon had two hits, Tyler Kinley (1-0) pitched an inning and Daniel Bard got the final three outs for his 10th save for the Rockies.

Colorado ended an eight-game home skid to San Francisco and a 12-game losing streak overall to the NL West Division rivals.

Thairo Estrada went 3-for-3 and Mike Yastrzemski had two hits for the Giants.

The Rockies took the lead when Blackmon hit his sixth homer off the year leading off the bottom of the first inning. Two outs later, McMahon singled and scored on Brendan Rodgers’ double to right that made it 2-0.

San Francisco answered in the second.

Colorado starter Kyle Freeland hit Brandon Crawford and gave up a double to Estrada. Yastrzemski singled to drive in Crawford, while Estrada moved up to third. He scored on Austin Slater’s sacrifice fly to center that tied the game.

The Giants manufactured a go-ahead run in the fourth.

Yastrzemski led off with a hustle double, just beating the throw to second from center field. He went to third when Slater flew out to the wall in left. He scored on Darin Ruf’s sacrifice fly to right to give San Francisco a 3-2 lead.

Freeland gave up three runs on seven hits and struck out eight in six innings.

Giants starter Logan Webb walked two batters in the bottom of the second and then settled in. He retired the next 16 batters he faced before Connor Joe led off the bottom of the eighth with a single, which ended Webb’s day.

Blackmon followed Joe with a sacrifice bunt off reliever Jose Alvarez (1-1) and Yonathan Daza tied it with a single. Cron then hit his 10th homer of the season to put the Rockies ahead.

Webb allowed three runs on four hits and struck out six in seven-plus innings.

–Field Level Media

Detroit Tigers left-hander Eduardo Rodriguez departed Wednesday’s start against the Tampa Bay Rays after seven batters due to left side discomfort and is headed to the 10-day injured list.

Tigers manager A.J. Hinch said Rodriguez will undergo an MRI exam to determine the severity.

Rodriguez recorded just one out before signaling to the dugout that he couldn’t continue. He said he began having troubles while warming up in the bullpen.

“When I was warming up in the bullpen, I felt a pinch on my side,” Rodriguez said after the 6-1 loss. “I wasn’t able to throw the ball as hard as I can. We’re going to see what it is, and we’ll see from there. … I’m going to check with the doctors and everything, then we’ll see what it is.”

The 29-year-old Rodriguez gave up three runs, four hits and two walks in the abbreviated 23-pitch outing.

“He said he could go,” Hinch said. “He never really felt anything during the week and increasingly got worse during his warmup. He tried to go out there. You could kind of tell he was off.”

Rodriguez is in his first season with the Tigers after signing a five-year, $77 million deal as a free agent. He is 1-3 with a 4.38 ERA in eight starts.

Rodriguez spent his first six big league seasons with the Boston Red Sox and won a career-high 19 games in 2019.

–Field Level Media

Pirates catcher Roberto Perez will undergo season-ending surgery on his injured hamstring, putting a premature end to his first season in Pittsburgh after just 21 games.

The Pirates said the surgery will likely take place later in the week. Perez was put on the 10-day injured list May 7 before the team transferred him to the 60-day IL.

Perez signed a one-year deal worth $5 million with Pittsburgh ahead of the lockout. He was to be the replacement for Jacob Stallings in 2022.

Perez, 33, was batting .233 with two home runs and eight RBIs in 60 at-bats. He spent the first eight seasons of his career in Cleveland. He is a two-time Gold Glove winner and career .207 hitter.

–Field Level Media

New York Yankees catcher Ben Rortvedt is recovering from arthroscopic surgery on his left knee.

Team physician Dr. Christopher Ahmad performed a meniscus clean-up procedure Tuesday in New York.

Rortvedt, 24, is expected to be sidelined for 6-8 weeks.

He began the season on the 10-day injured list with a strained right oblique muscle. He started a rehab assignment with Class-A Tampa on May 7 but was shut down after two games with discomfort in the knee.

Rortvedt, 24, batted .169 with three homers and seven RBIs in 39 games with the Minnesota Twins last season. He joined the Yankees in a March 13 trade that sent Josh Donaldson and Isiah Kiner-Falefa to New York for Gary Sanchez and Gio Urshela.

–Field Level Media

Isaac Paredes popped a pair of homers, starter Drew Rasmussen posted five scoreless frames and the Tampa Bay Rays surged past the Detroit Tigers 6-1 in a Wednesday matinee game in St. Petersburg, Fla.

Acquired in a trade with Detroit on April 4 for Austin Meadows, Paredes went deep in the third and eighth innings for his first multi-homer game.

Over an 87-pitch outing, Rasmussen (4-1) allowed a pair of hits in the first inning but only two more over the next four innings. He whiffed seven without a walk.

Tampa Bay improved to 14-4 in the right-hander’s 18 career starts.

In the Rays’ series-clinching win, Francisco Mejia drove in two runs in a three-run first, and Yandy Diaz (three singles) and Harold Ramirez (two) had multi-hit games.

Stolen bases by Wander Franco and Brett Phillips boosted the team’s total to 31, one behind the St. Louis Cardinals for most in the majors. The Cardinals play later Wednesday.

In his 14th career start against them, Detroit’s Eduardo Rodriguez (1-3) could manage just one out in the first before being replaced by Rony Garcia. The left-hander left while being accompanied by the team trainer after surrendering three runs, four hits and two walks.

Tigers manager A.J. Hinch said afterward that Rodriguez had discomfort in his left side, will undergo an MRI exam and is headed to the injured list.

Spencer Torkelson notched a homer and a double, but the Tigers were outhit 11-5 by the Rays.

Against a familiar foe in Rodriguez, a former member of the division rival Boston Red Sox, the Rays got to the Venezuelan hurler right away, with the first five batters reaching base as they batted around.

After packing the bases with three consecutive singles, Randy Arozarena produced the first run by drawing a four-pitch walk, then Mejia plated two runs with a single to left to make it 3-0.

Paredes struck the game’s loudest blow in the third with his first homer for his new club. The former Tiger ripped a 411-foot shot off Garcia’s four-season fastball for a 4-0 lead.

Rasmussen turned his game up a notch after allowing a leadoff double to Torkelson in the fifth. He got a groundout from Tucker Barnhart to end an 11-pitch at-bat, fanned Derek Hill on a high fastball with Torkelson on third and recorded a deep flyout by Robbie Grossman to keep the Tigers scoreless.

In the seventh, Torkelson was able to put Detroit on the board with a homer to left-center, his fourth long ball, but pinch hitter Ji-Man Choi answered with an RBI single in the bottom of the inning for Tampa Bay.

–Field Level Media

Keston Hiura hit a walk-off, two-run home run in the bottom of the 11th inning as the Milwaukee Brewers earned a 7-6 win against the visiting Atlanta Braves on Wednesday afternoon in the finale of their three-game series.

After Travis d’Arnaud hit a go-ahead single to put the Braves up 6-5, Hiura led off the home 11th with a blast over the center-field wall, plating ghost runner Jace Peterson to give the Brewers the series win.

The Braves blew leads in the 9th, 10th and 11th innings.

Atlanta once led 4-0, but Milwaukee stormed all the way back.

Trailing 4-3, Kolten Wong tied things up in the bottom of the ninth, lacing an RBI triple down the right-field line with two outs to send the game into extra innings.

The Braves took a lead in the 10th after Wong made a throwing error that allowed Ronald Acuna Jr. to score, but Hunter Renfroe’s sacrifice fly tied things once again.

Renfroe went 2-for-3 with a double and a walk, and has now hit safely in six of his last seven games. Tyrone Taylor went 2-for-5 with a pair of singles.

Atlanta got its offense going with a two-out rally in the top of the third.

Acuna was hit by a pitch and Matt Olson singled. Austin Riley then blasted his eighth home run of the season, a three-run shot, to break the scoreless tie. Marcell Ozuna followed with a solo homer to put the Braves up 4-0.

Riley and Ozuna both finished 2-for-5 on the afternoon. Olson went 2-for-4 with a double and a walk.

Milwaukee kept things close, plating a pair of runs in their half of the fourth thanks to back-to-back RBI singles from Taylor and Rowdy Tellez.

An RBI double from Mike Brosseau in the sixth later brought the Brewers within one.

Max Fried notched his fifth quality start across his last six outings for the Braves, allowing seven hits and three earned runs across six innings of work. He walked two and struck out six. Jesse Chavez (0-1) took the loss.

Trevor Kelley (1-0) earned the win in relief for Milwaukee.

Brewers starter Corbin Burnes went six innings, allowing seven hits and four earned runs. The right-hander issued no walks while striking out five.

–Field Level Media

Cleveland Guardians manager Terry Francona has cleared Major League Baseball’s health and safety protocol and is expected to be in the dugout for Wednesday’s game against the visiting Cincinnati Reds.

Francona, who missed four games, will be joined by bench coach DeMarlo Hale. Both tested positive for COVID-19 last week.

Sandy Alomar Jr. and Mike Sarbaugh, the Guardians’ first- and third-base coaches, respectively, as well as assistant pitching coach Joe Torres remain in the protocol. Hitting coach Chris Valaika returned to the team before Tuesday’s 5-4 setback in 10 innings against the Reds.

Pitching coach Carl Willis served as acting manager in Francona’s absence.

The Guardians have lost four of their last five games.

–Field Level Media

Scott Boras says he won’t negotiate an extension for Boston Red Sox shortstop Xander Bogaerts during the season.

“That’s our stance. I look forward to talking to John (Henry) and Tom (Werner) about Xander after the season,” the agent told the Boston Globe on Tuesday, referencing the team’s owners.

Bogaerts, 29, entered Wednesday batting .338 with three homers and 15 RBIs in 35 games this season.

The Red Sox reportedly offered the three-time All-Star a four-year, $90 million extension during spring training. His asking price is said to be in the $30-$35 million per year range, however.

Appearing on NESN on Tuesday, Red Sox chief baseball officer Chaim Bloom reiterated that the team wants to sign Bogaerts to a long-term deal.

“Obviously, we didn’t come to any sort of extension agreement before the season,” Bloom said. “I think the important thing is that we know Xander wants to be here, we want him to be here. We don’t have an agreement yet. But we’re trying to stay focused on the task at hand and that’s what we’re all doing. We know where everybody wants this to end up and we’ve got time to see what happens here.”

Bogaerts is in the third year of a six-year, $120 million extension signed in April 2019.

The two-time World Series winner is a career .291/.355/.459 hitter with 144 homers and 625 RBIs in 1,149 games with the Red Sox since 2013.

–Field Level Media

The Kansas City Royals expect to be without perennial All-Star catcher Salvador Perez for at least two weeks with a sprained left thumb.

He could be out as long as 4-6 weeks.

The injury occurred during Perez’s first at-bat Tuesday in Game 1 of a doubleheader against the Chicago White Sox. Perez said he sprained the thumb while swinging the bat. Perez, serving as the designated hitter in Game 1, left the game in the seventh inning because he couldn’t grip the bat.

The Royals put Perez on the10-day injured list between the two games and recalled catcher Sebastian Rivero from Double-A Northwest Arkansas.

“It’s the inside of my thumb, a grade 2 (sprain),” Perez said, per the Kansas City Star. “The ligament got turned. I just need some time off. Hopefully, it’s just 10 days. (Head trainer Kyle Turner) told me maybe it’s going to be four to six weeks, at least 21 days. It’s grade 2.”

Royals rookie MJ Melendez was forced to catch both games of Tuesday’s doubleheader.

Perez, 32, is batting just .206 with six homers and 16 RBIs in 34 games. The seven-time All-Star and five-time Gold Glove winner slugged 48 homers last season and is a career .268 hitter.

–Field Level Media

Chicago White Sox ace right-hander Lucas Giolito will start Wednesday’s game against the host Kansas City Royals after being reinstated from the COVID-19 injured list.

The White Sox also optioned Davis Martin to Triple-A Charlotte and transferred fellow right-hander Lance Lynn to the 60-day injured list.

Giolito, who was placed on the injured list last Friday, owns a 2-1 record with a 2.70 ERA in five starts this season.

Giolito, 27, is 44-39 with a 4.13 ERA in 122 career appearances (120 starts) with the Washington Nationals and White Sox.

Martin, 25, took the loss in his major league debut on Tuesday despite allowing just one run on five hits in five innings.

Lynn, 35, has been sidelined since spring training after undergoing surgery to repair a torn tendon in his right knee.

–Field Level Media