Masyn Winn and Jose Fermin smacked their first home runs, and the visiting St. Louis Cardinals clinched an interleague series win over the Houston Astros with a 7-5 victory on Saturday.

Alec Burleson also homered for the Cardinals, who pounced on Astros starter Lance McCullers Jr. (1-1) and rode a solid start from right-hander Andre Pallante (2-1), who worked five innings.

The Astros lost their third consecutive game and have dropped 11 of 13.

McCullers labored throughout his five-inning stint. He plunked JJ Wetherholt and Ivan Herrera with pitches to begin his outing and, after walking Jordan Walker to load the bases with one out in the top of the first inning, surrendered a single to Nolan Gorman that plated Wetherholt and Herrera and spotted the Cardinals a 2-0 lead.

McCullers issued walks to Fermin and Wetherholt but stranded both in the second. But with Gorman on first and one out in the third, McCullers grooved a 2-0 sinker that Winn launched into the left field seats. That 373-foot blast extended the Cardinals’ lead to 4-1. McCullers allowed four runs on four hits and three walks with four strikeouts. He threw 91 pitches, 58 for strikes.

Yordan Alvarez crushed his league-leading ninth home run to straightaway center with one out in the bottom of the first. Pallante limited the Astros to that lone tally by working around two baserunners in the second and third innings, and stranding Cam Smith at first in the fourth.

Pallante retired the side in order in the fifth, recording strikeouts of Jose Altuve and Carlos Correa in the frame. He allowed three hits and issued three walks while notching five strikeouts.

The Cardinals tacked on solo runs in the sixth, seventh and eighth innings. Fermin won a 10-pitch battle with Astros left-hander Colton Gordon with his 370-foot shot to left-center that pushed the Cardinals to a 5-1 lead. Burleson led off the seventh with his third homer, a 408-foot blast into the second deck in right field.

Shay Whitcomb slugged a three-run home run off Cardinals reliever George Soriano in the ninth, but closer Riley O’Brien retired Altuve and Alvarez to earn his sixth save.

–Field Level Media

Cedric Mullins’ two-run leadoff home run in the top of the 13th inning made the difference in an 8-7 victory for the Tampa Bay Rays against the Pirates to end a marathon game in Pittsburgh on Saturday night.

The four-hour, 12-minute game was the longest of the season in terms of innings played. It was extended by a two-hour, 27-minute weather delay.

Mullins had two hits and three RBIs and Jonny DeLuca had two hits and two RBIs to help the Rays rally from a 4-0 deficit before the delay and win for the seventh time in their past eight games. Mullins’ 403-foot homer to right field came off Yohan Ramirez (2-1).

The Pirates cut the deficit to one in the bottom of the 13th when Konnor Griffin singled home Jake Mangum. But Yoendrys Gomez recovered by striking out Joey Bart with runners on second and third to pick up his second career save and first of the season.

Chandler Simpson, Junior Caminero and Jonathan Aranda also had two hits each for Tampa Bay, which used eight relievers, capped by Griffin Jax (1-2) and Gomez.

Ryan O’Hearn and Marcell Ozuna each hit two-run home runs off Rays starter Drew Rasmussen with two outs in the first and fourth innings, respectively, to give the Pirates a 4-0 lead. The game was halted by rain during the ensuing at-bat by Spencer Horwitz.

When play resumed, Cam Sanders took over for Pirates ace Paul Skenes, who threw four scoreless innings, allowed three hits and struck out five on 64 pitches.

The Rays scored five runs in the top of the fifth to take a 5-4 lead.

Sanders walked Hunter Feduccia to open the inning, but appeared ready to get through it unscathed after striking out Taylor Walls and Simpson.

Caminero roped a double to left that scored Feduccia to put the Rays on the board. It was the first of five consecutive hits for Tampa Bay as Aranda drove home Caminero with a single. Two batters later, Aranda and Yandy Diaz scored on a double by DeLuca off reliever Evan Sisk to tie the game at 4. Mullins then drove in the go-ahead run with a single.

–Field Level Media

Brayan Rocchio hit a three-run homer and Gavin Williams pitched seven strong innings to lead the Cleveland Guardians to a 4-2 victory over the visiting Baltimore Orioles on Saturday.

Bo Naylor also homered for the Guardians, who won for just the second time in the past five games. Cleveland had just three hits.

Williams (3-1) struck out 11 and allowed one run, three hits and one walk. It marked the second time this season and sixth time overall that he has struck out 10 or more in a game.

Cade Smith fanned the side in the ninth for his fifth save.

Leody Taveras and Gunnar Henderson (two hits) hit solo homers for Baltimore, which had just four hits while losing for the fourth time in the past five games.

Dean Kremer (0-1) pitched six innings for the Orioles and gave up three runs and two hits. He struck out seven and walked two.

Baltimore’s Pete Alonso and Colton Cowser struck out in all four at-bats. Dylan Beavers fanned three times as 16 Orioles went down on strikes.

Taveras came up with one out in the fourth and drilled a 1-0 curveball from Williams over the fence to right for the game’s first run.

Meanwhile, Kremer tossed 4 1/3 no-hit innings and his walk to Rhys Hoskins was followed by Daniel Schneemann’s line single to right. After Naylor fanned, Rocchio jumped on a 2-2 fastball from Kremer and deposited the ball over the fence in right to give the Guardians a 3-1 lead.

Williams picked up where he left off after the Taveras homer by retiring the final 11 batters he faced.

Hunter Gaddis replaced Williams and Henderson touched him up for a one-out solo shot to right in the eighth.

But Naylor got the run back leading off the bottom of the inning when he launched a 1-1 changeup from Albert Suarez into the bleachers in right.

Smith fanned Beavers, Cowser and Taveras while closing it out as Cleveland gained a 2-1 edge in a series that concludes Sunday.

–Field Level Media

Brice Turang slugged a go-ahead, two-run homer and Brandon Woodruff pitched seven brilliant innings as the Milwaukee Brewers beat the host Miami Marlins 5-2 on Saturday afternoon.

Abner Uribe inherited a bases-loaded, one-out mess in the ninth. However, he retired both batters he faced on only four pitches to record his second save.

Turang went 2-for-3 with three RBIs for Milwaukee, which won its season-high fourth consecutive game.

Woodruff (2-0) allowed just three hits — all singles — one walk and one run, lowering his ERA to 3.42. He fanned four Marlins.

Miami has lost four straight and seven of its past eight games.

Marlins starter Sandy Alcantara (2-2) allowed five hits and three runs in five innings. He walked a career-high-tying six batters and struck out just one, tying a career low in a start of at least five innings for the nine-year veteran.

Miami opened the scoring in the second inning as Liam Hicks singled, advanced on a groundout and scored on Connor Norby’s base knock to center.

Milwaukee loaded the bases with one out in the third on three walks, but Alcantara got the slow-footed Gary Sanchez to bounce into a double play.

The Brewers tied the score in the fourth as Luis Rengifo walked and scored on Brandon Lockridge’s two-out single.

Milwaukee grabbed a 3-1 lead in the fifth as William Contreras grounded a hustle double past two middle infielders and scored on Turang’s 402-foot homer to center. He hit a first-pitch slider for his fourth long ball of the year.

The Brewers extended their lead to 5-1 in the sixth. Garrett Mitchell started the rally with a walk. He stole second, advanced to third on a wild pitch and scored on an RBI groundout by Sal Frelick. Mitchell was initially called out, but the Brewers won a challenge.

Turang then hit an RBI single to score Joey Ortiz, who had also walked.

Miami threatened in the eighth on a pair of two-out singles by Jakob Marsee and Xavier Edwards. But reliever Jake Woodford got Agustin Ramirez to ground out, ending the inning.

In the ninth, the Marlins loaded the bases with one out, banging three singles against Woodford. Uribe got Heiberto Hernandez to ground to third base, plating Otto Lopez, then retired Javier Sanoja on a grounder to second.

Hicks and Norby had two hits apiece for Miami.

–Field Level Media

Matt Chapman drove in the go-ahead run in the top of the 12th inning and the San Francisco Giants beat the host Washington Nationals 7-6 on Saturday.

Chapman led off the 12th against Cionel Perez (0-2) and grounded a single to left, scoring automatic runner Luis Arraez.

Caleb Kilian (1-0) pitched two innings for the win. The automatic runner did not advance in either inning and Kilian only allowed one baserunner on an intentional walk.

The Nationals loaded the bases with no outs in the 10th, but Ryan Walker got two strikeouts and a groundout.

Heliot Ramos had three hits including his second home run in two games as San Francisco won its third straight.

James Wood hit his seventh homer of the season and scored three runs for the Nationals.

With Washington trailing 6-5 in the ninth, Jorbit Vivas doubled against Walker leading off and went to third on a flyout. After Wood was walked intentionally, Curtis Mead hit a grounder and Vivas was thrown out at home. Brady House tied the game when he blooped single to center and Wood scored before Mead was thrown out at third.

Wood led off the bottom of the first and homered to give Washington a 1-0 lead.

Jung Hoo Lee singled with one out in the second and Ramos doubled, but Lee was thrown out at home. Drew Gilbert followed with a single to right, plating Ramos with the tying run.

The Nationals loaded the bases as the first three batters reached in the second. Drew Millas grounded into a force at home, but Wood was hit by a pitch to force in a run. Luis Garcia Jr. singled in two runs and Jose Tena singled in another to make it 5-1.

An error by third baseman Vivas gave the Giants runners on first and second with one out in the third and Casey Schmitt lined a two-out double to left that scored two runs, one coming across on a fielding error by Daylen Lile.

Lee singled off Parker with one out in the sixth and Ramos followed with a shot to left to tie it.

Willy Adames singled leading off the seventh and went to second on a wild pitch. Rafael Devers lined a two-out single to left, scoring Adames to give the Giants a 6-5 lead.

Giants starter Adrian Houser gave up five runs (four earned) on seven hits over 5 2/3 innings. His Nats counterpart Cade Cavalli gave up three runs (one earned) on seven hits in four innings.

–Field Level Media

Tarik Skubal pitched six dominant innings and Kerry Carpenter highlighted his multi-hit game with a home run, leading the Detroit Tigers to a 4-1 win over the host Boston Red Sox on Saturday afternoon.

Skubal (3-2) struck out 10, twice fanning the side, while allowing just one run on four hits.

Carpenter (2-for-3, two RBIs) and Kevin McGonigle (2-for-5, RBI, run) led the offense for Detroit, which broke a nine-game road losing streak.

Tyler Holton and Kenley Jansen teamed up in relief as Boston was limited to five hits. Jansen notched his fifth save.

Brayan Bello (1-2) gave up four runs on five hits and three walks in four innings. He fanned four, while throwing 84 pitches.

The Tigers grabbed a 1-0 lead in the first inning while forcing Bello to throw 35 pitches. After McGonigle lined a leadoff single to right, another base knock by Colt Keith and a walk to Riley Greene loaded the bases.

Bello fanned Spencer Torkelson, but another free pass to Carpenter forced home Detroit’s opening run.

Bello retired the next eight men he faced, including a strikeout to begin the fourth, before the visitors marked the scoreboard again on Carpenter’s towering homer into the right-center field bullpen. After two more baserunners continued the line, Jake Rogers’ sacrifice fly and another McGonigle single extended the Detroit lead.

The four runs proved to be enough support for Skubal, who retired the Red Sox in order the first time through the lineup and allowed just one baserunner before Boston got on the board in the fifth.

In the hosts’ run-scoring inning, a Wilyer Abreu single and Ceddanne Rafaela double set the table in the inning, but Connor Wong’s double play ball plating a run was all of the offense Skubal would allow.

Back-to-back hits by Roman Anthony and Andruw Monestario to begin the sixth gave Boston an opportunity to break into its deficit further, but Skubal escaped trouble with two strikeouts of the next three batters.

Skubal fanned the side in the second and fourth innings. Boston’s Willson Contreras and Trevor Story each struck out three times in the game.

–Field Level Media

Nick Kurtz hit a game-tying home run in the seventh inning and Max Muncy was the walk-off hero in the 11th as the Athletics overcame an early 5-0 deficit to beat the Chicago White Sox 7-6 on Saturday afternoon in West Sacramento, Calif.

Muncy hit a game-winning sacrifice fly to left field off Lucas Sims (0-2) to score Jacob Wilson and complete the comeback.

The White Sox had the bases loaded with no outs in the top of the 11th, but Jack Perkins (2-0) pitched out of trouble to give the A’s a chance to end the game in the bottom half.

The game went to extras after Kurtz’s two-run shot off Jordan Leasure in the seventh.

Colson Montgomery, Andrew Benintendi and Munetaka Murakami hit home runs in a losing effort for Chicago. The White Sox missed countless chances to build on their lead, finishing 3-for-17 with runners in scoring position.

Chicago was in control after a five-run second. Montgomery’s fourth home run came on the first pitch of the inning. The barrage continued with a bloop RBI single for Reese McGuire and Benintendi’s three-run homer.

Athletics starter Luis Severino settled down after that, allowing no further damage over the remainder of his 5 1/3 innings. He finished with five runs, five hits and four walks allowed to go with three whiffs.

Jacob Wilson started the home team’s reply with a solo home run to left with one out in the second.

Lawrence Butler went station-to-station to add a run in the third. He drew a leadoff walk, stole second, advanced to third on an Austin Wynns groundout and scored on Jeff McNeil’s sac fly.

White Sox starter Erick Fedde was pulled after 4 2/3 innings. He had an erratic outing with four walks, one wild pitch and three runs allowed.

Sean Newcomb relieved Fedde with two runners on base and allowed a third unanswered A’s run when Tyler Soderstrom hit an RBI single.

Muncy hit a one-out triple in the sixth and scored when Newcomb couldn’t field a slow roller by Butler cleanly, cutting the White Sox advantage to 5-4.

Chicago added some breathing space when Murakami hit his second home run in as many games to lead off the seventh, but the Athletics answered swiftly as Shea Langeliers opened the bottom of the inning with a single and Kurtz lined a rope over the right field fence to make it 6-6.

–Field Level Media

Pinch hitter Dane Myers’ bloop single scored Spencer Steer in the top of the ninth inning as the Cincinnati Reds rallied for a 5-4 win over the Minnesota Twins on Saturday in Minneapolis.

Kyle Nicolas (1-0) struck out all three batters in the eighth inning for Cincinnati. Tony Santillan pitched a 1-2-3 bottom of the ninth and earned his first save of the season as the Reds have won the first two games of the three-game set.

Minnesota manager Derek Shelton was ejected in the top of the seventh after Elly De La Cruz’s RBI single scored Rece Hinds to trim the Twins’ lead to 4-3. Shelton was upset De La Cruz was ruled to have checked his swing a pitch earlier.

An inning later, the Reds tied the game at 4 when Hinds’ sacrifice fly scored Eugenio Suarez. Cole Sands (0-1) allowed Myers’ game-winning hit in the ninth.

Minnesota took a 2-0 lead in the bottom of the first inning. Austin Martin walked with one out and Josh Bell singled to right. Ryan Jeffers knocked them both in with a triple to the left-center gap. Bell and Luke Keaschall each collected two hits for the Twins.

Tyler Stephenson’s sacrifice fly to center field scored Sal Stewart and cut the Twins’ lead to 2-1 in the top of the second.

In the bottom of the third, Martin reached on an error and was eventually plated on Keaschall’s line drive to shallow right field to push Minnesota’s lead to 3-1.

Cincinnati pulled within 3-2 in the top of the fourth. Suarez doubled with one out and moved to third on Nathaniel Lowe’s ground out. On an 0-2 pitch, Stephenson drove a hanging cutter into left field for a single to score Suarez. Suarez and Lowe both had two hits.

Bell led off the bottom of the fifth with a single. After a two-out walk to Trevor Larnach, the Reds went to the bullpen. Reliever Sam Moll gave up an RBI single to Brooks Lee that scored Bell to once again restore Minnesota’s two-run lead at 4-2.

Reds starting pitcher Andrew Abbott gave up four runs (three earned), six hits, walked three and struck out three in 4 2/3 innings. Twins starter Taj Bradley allowed two runs, five hits, walked two and struck out five in six innings.

–Field Level Media

Carson Kelly hit a tie-breaking three-run pinch-hit home run in the sixth inning Saturday afternoon for the host Chicago Cubs, who beat the skidding New York Mets 4-2.

The pinch-hit homer was the second of Kelly’s career and his first since Aug. 25, 2021, when he went deep for the Arizona Diamondbacks against the Pittsburgh Pirates’ Anthony Banda.

Ian Happ homered in the second for the Cubs, who have won four straight and have scored 51 runs while winning five of their last six games. Chicago scored 59 runs in its first 14 games this season.

Kelly’s homer off Brooks Raley made a winner of Jameson Taillon (1-1), who gave up one run on five hits and three walks while striking out four over six innings.

Mark Vientos provided the visitors a short-lived lead by homering in the top of the second for the Mets, who have lost 10 straight — their longest skid since an 11-game losing streak from Aug. 28-Sept. 8, 2004. New York hasn’t led at the end of an inning since the first inning of an 11-6 loss to the Athletics on April 11 — a span of 62 frames.

New York’s Bo Bichette scored when second baseman Nico Hoerner threw wide of the bag on Francisco Alvarez’s two-out grounder in the eighth. But reliever Ben Brown induced Vientos to ground out to third and strand two before Caleb Thielbar struck out two in a perfect ninth to earn his first save of 2026.

Freddy Peralta (1-2) took the loss after allowing three runs on three hits and two walks while striking out three over 5 2/3 innings. Peralta issued both walks with two outs in the sixth, after which Kelly took Raley deep on the first pitch he saw. The homer was the first surrendered by Raley since 2023.

The Cubs only managed five hits as Happ reached in 3-of-4 plate appearances with a pair of walks.

Francisco Lindor and Luis Robert Jr. had two hits apiece for the Mets, who were 0-for-6 with runners in scoring position.

–Field Level Media

The Philadelphia Phillies placed closer Jhoan Duran on the 15-day injured list Saturday with a left oblique strain.

In a series of moves, right-hander Seth Johnson and utilityman Felix Reyes were recalled from Triple-A Lehigh Valley, while utilityman Otto Kemp was optioned and minor league outfielder Pedro Leon was released.

Duran’s move to the IL was retroactive to Wednesday. The 28-year-old right-hander is 1-1 with a 1.35 ERA and five saves in seven appearances for the Phillies this season. Over five major league seasons with the Minnesota Twins and Phillies, he has a 2.41 ERA and 95 saves in 253 appearances.

Johnson, 27, made one appearance with the Phillies earlier this season and has a combined 9.72 ERA in 12 appearances (one start) for Philadelphia over three seasons.

Reyes, 25, is set to make his major league debut after he batted .272 with 48 home runs and 247 RBIs over six seasons (374 games) in the Phillies’ system. Kemp, 26, was 2-for-20 in 10 games for Philadelphia this season.

Leon, 27, was batting .283 in 12 games at Lehigh Valley. He has seven games of major league experience with the Houston Astros in 2024.

–Field Level Media