Houston Texans running back Joe Mixon was placed on the non-football injury list Wednesday.

A Pro Bowl selection during his first season in Houston, Mixon has yet to participate in practice during organized team activities and minicamp due to an ankle injury.

Mixon, who turns 29 on Thursday, rushed for 1,016 yards and 11 touchdowns in 14 games (all starts) last season.

He has rushed for 7,428 yards and 60 touchdowns in 111 career games (102 starts) with the Cincinnati Bengals (2017-23) and Texans. He earned his second Pro Bowl selection in 2024.

Houston’s backfield also includes offseason additions Nick Chubb, Dare Ogunbowale and rookie Woody Marks, among others. Marks was selected by Houston in the fourth round of the 2025 NFL Draft out of Southern California.

Fellow running backs Dameon Pierce and J.J. Taylor joined wide receiver Tank Dell, defensive ends Derek Barnett and Denico Autry, safety Jimmie Ward, offensive tackle Trent Brown, defensive tackles Folorunso Fatukasi and Kurt Hinish, linebacker K.C. Ossai and center Eli Cox in being placed on the physically unable to perform list Wednesday.

–Field Level Media