The San Francisco 49ers have promoted quarterback Adrian Martinez from the practice squad to the active roster ahead of Thursday night’s road game against the Los Angeles Rams.

The 49ers (3-1) already had ruled out quarterback Brock Purdy (turf toe), making Mac Jones the starter against the Rams (3-1). Jones started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

Receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive end Robert Beal Jr. (ankle) also were declared out after not practicing this week.

Martinez, 25, has not appeared in an NFL regular-season game. The 49ers signed him to their practice squad on Aug. 28 after he was waived by the New York Jets. He spent time on the Jets’ practice squad in 2024 and also was in camp with the Detroit Lions in 2023.

In other moves on Thursday, San Francisco elevated defensive lineman Trevis Gipson and wide receiver Malik Turner from the practice squad for game day, signed cornerback Derrick Canteen to the practice squad and waived defensive lineman Jordan Jefferson.

Gipson, 28, was a fifth-round pick of the Chicago Bears in the 2020 NFL Draft. He has 81 career tackles, including 11 sacks, in 53 regular-season games (19 starts) for the Bears (2020-22), Tennessee Titans (2023) and Seattle Seahawks (2024).

Turner, 29, has 29 career receptions for 414 yards and four touchdowns in 45 regular-season games (three starts) for the Seahawks (2018-19), Dallas Cowboys (2020-2021) and 49ers (2022, 2025).

Jefferson, 24, was selected by the Jacksonville Jaguars in the fourth round of the 2024 draft. He played in one game this season for the 49ers and in eight for the Jaguars in 2024.

Canteen signed with the 49ers in May as an undrafted free agent out of the University of Cincinnati. He also played at Virginia Tech (2023) and Georgia Southern (2019-22).

–Field Level Media